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Rodney L Johnson Selected Research

3- (N- prolylamine)- 2- oxo- 1- pyrrolidineacetamide

4/2015Change in expression of vesicular protein synapsin II by chronic treatment with D2 allosteric modulator PAOPA.
4/2013Preclinical pharmacokinetic and toxicological evaluation of MIF-1 peptidomimetic, PAOPA: examining the pharmacology of a selective dopamine D2 receptor allosteric modulator for the treatment of schizophrenia.
3/2013PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioral and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia.
1/2013Effects of the dopamine D2 allosteric modulator, PAOPA, on the expression of GRK2, arrestin-3, ERK1/2, and on receptor internalization.
12/2005Modulation of agonist binding to human dopamine receptor subtypes by L-prolyl-L-leucyl-glycinamide and a peptidomimetic analog.

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Rodney L Johnson Research Topics

Disease

5Schizophrenia (Dementia Praecox)
04/2015 - 03/2010
2Anthrax
12/2015 - 11/2015
2Parkinson Disease (Parkinson's Disease)
03/2010 - 10/2007
2Tardive Dyskinesia
03/2010 - 10/2007
1Bacterial Infections (Bacterial Infection)
12/2015
1AIDS-Related Complex (ARC)
11/2014
1Mental Disorders (Mental Disorder)
03/2013
1Neuroblastoma
12/2005

Drug/Important Bio-Agent (IBA)

53- (N- prolylamine)- 2- oxo- 1- pyrrolidineacetamideIBA
04/2015 - 12/2005
3Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
04/2013 - 01/2013
2PeptidomimeticsIBA
04/2013 - 10/2007
2glycine amideIBA
10/2007 - 12/2005
1ExotoxinsIBA
12/2015
1ZincIBA
11/2015
1EnzymesIBA
11/2015
1HydrolasesIBA
11/2015
1Proteins (Proteins, Gene)FDA Link
04/2015
1Therapeutic UsesIBA
04/2015
1Synapsins (Synapsin I)IBA
04/2015
1LigandsIBA
11/2014
1MSH Release-Inhibiting Hormone (MIF-I)IBA
04/2013
1Amphetamine (Amfetamine)FDA LinkGeneric
03/2013
1Dizocilpine Maleate (Dizocilpine)IBA
03/2013
1Dopamine Receptors (Dopamine Receptor)IBA
03/2010
1Melanocyte-Stimulating Hormones (MSH)IBA
10/2007
1Haloperidol (Haldol)FDA LinkGeneric
10/2007
1Oxidopamine (6 Hydroxydopamine)IBA
10/2007
1Trifluoroacetic Acid (Trifluoroacetate)IBA
10/2007
1ApomorphineFDA Link
10/2007
1Dopamine (Intropin)FDA LinkGeneric
12/2005

Therapy/Procedure

3Therapeutics
04/2015 - 03/2010